Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Application of C4H11NO.
Ratcliffe, Paul;MacLean, John;Abernethy, Lynn;Clarkson, Tom;Dempster, Maureen;Easson, Anna-Marie;Edwards, Darren;Everett, Katy;Feilden, Helen;Littlewood, Peter;McArthur, Duncan;McGregor, Deborah;McLuskey, Hazel;Nimz, Olaf;Nisbet, Lesley-Anne;Palin, Ronnie;Tracey, Heather;Walker, Glenn research published 《 Identification of potent, soluble, and orally active TRPV1 antagonists》, the research content is summarized as follows. Optimization of a water soluble, moderately potent lead series of isoxazole-3-carboxamides was conducted, affording a compound with the requisite balance of potency, solubility and physicochem. properties for in vivo use. Compound 8e was demonstrated to be efficacious in a rat model of inflammatory pain, following oral administration.
Application of C4H11NO, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem