Name: 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole, is researched, Molecular C17H19N3O2S, CAS is 73590-85-9, about Going Green in Process Chemistry: Optimizing an Asymmetric Oxidation Reaction To Synthesize the Antiulcer Drug Esomeprazole. Author is McAllister, Graeme D.; Parsons, Andrew F..
Sustainable practices in process chem. are highlighted by a novel, 9 wk team project of 8-12 students, in collaboration with AstraZeneca chemists, in an organic chem. laboratory Students synthesize the antiulcer medicine esomeprazole, which involves the asym. oxidation of pyrmetazole. To provide insight into the modern process chem. industry, they propose environmentally friendly modifications to the asym. oxidation Students first synthesize pyrmetazole and then follow a standard oxidation procedure and carry out modified, greener reactions of their choice. They investigate how a change in reaction conditions affects both the yield and enantioselectivity of esomeprazole. Pos. student feedback was received and student postlab reports were analyzed over a 4 yr period (2015-2018). Results consistently showed that the project provided students with the key tools to develop greener syntheses. This contextual approach not only offers the opportunity to develop valuable communication and team-working skills, but it also gives students creative input into their exptl. work. It teaches the important research skills involved in sustainable process chem., from reproducing and modifying a literature procedure to identifying green metrics.
After consulting a lot of data, we found that this compound(73590-85-9)Name: 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem