Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 73590-85-9, is researched, SMILESS is CC1=CN=C(CSC2=NC3=CC(OC)=CC=C3N2)C(C)=C1OC, Molecular C17H19N3O2SJournal, Heterocyclic Communications called An efficient asymmetric approach to the R-enantiomer impurity of esomeprazole, Author is Zhou, Guobin; Guan, Yueqing, the main research direction is esomeprazole preparation enantioselective.Application In Synthesis of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole.
The R-enantiomer of esomeprazole (5-methoxy-2-[(4-methoxy-3, 5-dimethyl-2-pyridinylmethyl)sulfinyl]-1H-benzimidazole) was synthesized with high enantioselectivity by asym. oxidation of prochiral sulfide using the oxaziridinium salt. This (R)-enantiomer, useful as a reference for the quality control of esomeprazole was characterized by 1H and 13CNMR, IR and HRMS. The enantiomeric excess was determined by HPLC.
After consulting a lot of data, we found that this compound(73590-85-9)Application In Synthesis of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem