Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 73590-85-9, is researched, SMILESS is CC1=CN=C(CSC2=NC3=CC(OC)=CC=C3N2)C(C)=C1OC, Molecular C17H19N3O2SJournal, Tetrahedron: Asymmetry called Asymmetric synthesis of esomeprazole, Author is Cotton, H.; Elebring, T.; Larsson, M.; Li, L.; Sorensen, H.; von Unge, S., the main research direction is esomeprazole asym synthesis.Formula: C17H19N3O2S.
A highly efficient synthesis of esomeprazole – the (S)-enantiomer of omeprazole – via asym. oxidation of prochiral sulfide I is described. The asym. oxidation was achieved by titanium-mediated oxidation with cumene hydroperoxide (CHP) in the presence of (S,S)-diethyl tartrate [(S,S)-DET]. The enantioselectivity was provided by preparing the titanium complex in the presence of I at an elevated temperature and/or during a prolonged preparation time and by performing the oxidation of I in the presence of an amine. An enantioselectivity of >94% ee was obtained using this method.
Compounds in my other articles are similar to this one(5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole)Formula: C17H19N3O2S, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.
Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem