The effect of reaction temperature change on equilibrium 56621-48-8

This literature about this compound(56621-48-8)Computed Properties of C10H14N2Ohas given us a lot of inspiration, and I hope that the research on this compound(4-(Piperazin-1-yl)phenol) can be further advanced. Maybe we can get more compounds in a similar way.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Efficient factors on the hydrolysis reaction rate of some para-aminophenol derivatives in acidic pHs, published in 2013, which mentions a compound: 56621-48-8, Name is 4-(Piperazin-1-yl)phenol, Molecular C10H14N2O, Computed Properties of C10H14N2O.

Electrochem. oxidation of some p-aminophenol derivatives (1-5) in acidic solutions was studied both exptl. and theor. to provide insight into the influence of some factors on the hydrolysis reaction rate. The result of this work shows that the electrogenerated p-quinoneimines participate in the hydrolysis reaction and are converted to the p-benzoquinone. The hydrolysis reaction rate strongly depends on the structure of the p-aminophenols and solution’s pH. The observed homogeneous rate constants of hydrolysis (kobshyd) of p-quinoneimines were determined using digital simulation technique. The effect of different parameters such as: change of Gibbs free energy (ΔG) of the electrochem. oxidation of para-aminophenol derivatives (1-5), charge of reaction site, N-C4 bond order (Wiberg Bond Indexes, WBIs) and the nature of substituted group, on the hydrolysis rate constant were also studied. All calculations were performed using D. Functional Theory (DFT) both BP86 and B3LYP levels of theory and 6-311G (p,d) basis set. The N-C4 bond order and charge on the reaction site play significant roles in hydrolysis reaction’s rate.

This literature about this compound(56621-48-8)Computed Properties of C10H14N2Ohas given us a lot of inspiration, and I hope that the research on this compound(4-(Piperazin-1-yl)phenol) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem