Recently I am researching about INHIBITORS; PET; SUBSTITUTION; ARYL; SITE; F-18-FLUORINATION; INFLAMMATION; DERIVATIVES; METABOLISM; REAGENT, Saw an article supported by the National Institutes of Health (NIGMS)United States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of General Medical Sciences (NIGMS) [RO1GM12018, 5R01EB014354]; UNC Department of Radiology, Biomedical Research Imaging Center; UNC Lineberger Comprehensive Cancer Center; NSF Graduate Research FellowshipNational Science Foundation (NSF); NIH High-End Instrumentation GrantUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USA [IS100D023611-01]; NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERINGUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of Biomedical Imaging & Bioengineering (NIBIB) [R01EB014354] Funding Source: NIH RePORTER; NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of General Medical Sciences (NIGMS) [R01GM120186] Funding Source: NIH RePORTER. Safety of Diphenyl oxide. Published in AMER ASSOC ADVANCEMENT SCIENCE in WASHINGTON ,Authors: Chen, W; Huang, Z; Tay, NES; Giglio, B; Wang, MZ; Wang, H; Wu, ZH; Nicewicz, DA; Li, ZB. The CAS is 101-84-8. Through research, I have a further understanding and discovery of Diphenyl oxide
Positron emission tomography (PET) plays key roles in drug discovery and development, as well as medical imaging. However, there is a dearth of efficient and simple radiolabeling methods for aromatic C-H bonds, which limits advancements in PET radiotracer development. Here, we disclose a mild method for the fluorine-18 (F-18)-fluorination of aromatic C-H bonds by an [F-18]F- salt via organic photoredox catalysis under blue light illumination. This strategy was applied to the synthesis of a wide range of F-18-labeled arenes and heteroaromatics, including pharmaceutical compounds. These products can serve as diagnostic agents or provide key information about the in vivo fate of the labeled substrates, as showcased in preliminary tracer studies in mice.
Safety of Diphenyl oxide. About Diphenyl oxide, If you have any questions, you can contact Chen, W; Huang, Z; Tay, NES; Giglio, B; Wang, MZ; Wang, H; Wu, ZH; Nicewicz, DA; Li, ZB or concate me.
Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem