Recommanded Product: 103-50-4. Recently I am researching about TUMOR MICROENVIRONMENT; PHOTODYNAMIC THERAPY; HIGHLY EFFICIENT; NANOSHEETS; SURFACE; AGENT, Saw an article supported by the National Research Programs of China [2016YFA0201200]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [51525203, 51761145041, 51572180]; Collaborative Innovation Center of Suzhou Nano Science and Technology; Jiangsu Natural Science Fund for Distinguished Young Scholars [BK20130005, BK20170063]; Priority Academic Program Development (PAPD) of Jiangsu Higher Education Institutions. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Gong, F; Cheng, L; Yang, NL; Betzer, O; Feng, LZ; Zhou, Q; Li, YG; Chen, RH; Popovtzer, R; Liu, Z. The CAS is 103-50-4. Through research, I have a further understanding and discovery of Benzyl ether
Sonodynamic therapy (SDT) triggered by ultrasound (US) has attracted increasing attention owing to its abilities to overcome critical limitations including low tissue-penetration depth and phototoxicity in photodynamic therapy. Herein, the design of a new type of sonosensitizer is revealed, namely, ultrasmall oxygen-deficient bimetallic oxide MnWOX nanoparticles, for multimodal imaging-guided enhanced SDT against cancer. As-made MnWOX nanoparticles with poly(ethylene glycol) (PEG) modification show high physiological stability and biocompatibility. Interestingly, such MnWOX-PEG nanoparticles exhibit highly efficient US-triggered production of O-1(2) and center dot OH, higher than that of previously reported sonosensitizers (e.g., protoporphyrin IX and titanium dioxide), because the oxygen-deficient structure of MnWOX serves as an electron trap site to prevent electron-hole recombination. The glutathione depletion capability of MnWOX-PEG can also further favor SDT-triggered cancer cell killing. With efficient tumor homing as illustrated by computer tomography and magnetic resonance imaging, MnWOX-PEG enables effective destruction of mouse tumors under US stimulation. After accomplishing its therapeutic functions, MnWOX-PEG can be metabolized by the mouse body without any long-term toxicity. Herein, a new type of sono-sensitizing agent with high SDT efficacy, multimodal imaging functions, and rapid clearance is presented, an agent which is promising for noninvasive SDT cancer treatment.
Recommanded Product: 103-50-4. About Benzyl ether, If you have any questions, you can contact Gong, F; Cheng, L; Yang, NL; Betzer, O; Feng, LZ; Zhou, Q; Li, YG; Chen, RH; Popovtzer, R; Liu, Z or concate me.
Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem