Month: October 2021

An article Psoralen Derivatives with Enhanced Potency WOS:000542397500001 published article about WAVELENGTH DEPENDENCE; FUROCOUMARIN DERIVATIVES; ACID PHOTOREACTION; CROSS-LINKING; DNA; 8-METHOXYPSORALEN; CELLS; PHOTOCHEMOTHERAPY; MONOADDUCTS; INHIBITION in [Buhimschi, Alexandru D.] Northwestern Univ, Feinberg Sch Med, Med Scientist Training Program, Chicago, IL 60611 USA; [Buhimschi, Alexandru D.; Gasparro, Francis P.] Hamden Hall Country Day Sch, Photobiol Lab, Hamden, CT 06517 USA; [Gooden, David M.] Duke Univ, Dept Chem, Durham, NC 27706 USA; [Jing, Hongwu] Univ Illinois, Coll Med, Dept Obstet & Gynecol, Chicago, IL 60612 USA; [Fels, Diane R.; Hansen, Katherine S.; Dewhirst, Mark W.] Duke Univ, Med Ctr, Dept Radiat Oncol, Durham, NC USA; [Fels, Diane R.; Hansen, Katherine S.; Dewhirst, Mark W.] Duke Univ, Med Ctr, Duke Canc Inst, Durham, NC USA; [Beyer, Wayne F., Jr.; Walder, Harold] Immunolight LLC, Detroit, MI USA in 2020.0, Cited 58.0. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8. Recommanded Product: Diphenyl oxide

Psoralen is a furocoumarin natural product that intercalates within DNA and forms covalent adducts when activated by ultraviolet radiation. It is well known that this property contributes to psoralen’s clinical efficacy in several disease contexts, which include vitiligo, psoriasis, graft-versus-host disease and cutaneous T-cell lymphoma. Given the therapeutic relevance of psoralen and its derivatives, we attempted to synthesize psoralens with even greater potency. In this study, we report a library of 73 novel psoralens, the largest collection of its kind. When screened for the ability to reduce cell proliferation, we identified two derivatives even more cytotoxic than 4 ‘-aminomethyl-4,5 ‘,8-trimethylpsoralen (AMT), one of the most potent psoralens identified to date. Using MALDI-TOF MS, we studied the DNA adduct formation for a subset of novel psoralens and found that in most cases enhanced DNA binding correlated well with cytotoxicity. Generally, our most potent derivatives contain positively charged substituents, which we believe increase DNA affinity and enhance psoralen intercalation. Thus, we provide a rational approach to guide efforts toward further optimizing psoralens to fully capitalize on this drug class’ therapeutic potential. Finally, the structure-activity insights we have gained shed light on several opportunities to study currently underappreciated aspects of psoralen’s mechanism.

About Diphenyl oxide, If you have any questions, you can contact Buhimschi, AD; Gooden, DM; Jing, HW; Fels, DR; Hansen, KS; Beyer, WF; Dewhirst, MW; Walder, H; Gasparro, FP or concate me.. Recommanded Product: Diphenyl oxide

Reference:
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Category: ethers-buliding-blocks. Recently I am researching about HARMONIC VIBRATIONAL FREQUENCIES; SCALE FACTORS; ORGANIC LIQUIDS; SPECTROSCOPY; DENSITY; ENERGY; IR; FUNCTIONALS; COEFFICIENT; MOLECULES, Saw an article supported by the eSSENCE. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Henschel, H; Andersson, AT; Jespers, W; Ghahremanpour, MM; van der Spoel, D. The CAS is 101-84-8. Through research, I have a further understanding and discovery of Diphenyl oxide

Infrared spectroscopy can provide significant insight into the structures and dynamics of molecules of all sizes. The information that is contained in the spectrum is, however, often not easily extracted without the aid of theoretical calculations or simulations. We present here the calculation of the infrared spectra of a database of 703 gas phase compounds with four different force fields (CGenFF, GAFF-BCC, GAFF-ESP, and OPLS) using normal-mode analysis. Modern force fields increasingly use virtual sites to describe, e.g., lone-pair electrons or the o -holes on halogen atoms. This requires some adaptation of code to perform normal-mode analysis of such compounds, the implementation of which into the GROMACS software is briefly described as well. For the quantitative comparison of the obtained spectra with experimental reference data, we discuss the application of two different statistical correlation coefficients, Pearson and Spearman. The advantages and drawbacks of the different methods of comparison are discussed, and we find that both methods of comparison give the same overall picture, showing that present force field methods cannot match the performance of quantum chemical methods for the calculation of infrared spectra.

About Diphenyl oxide, If you have any questions, you can contact Henschel, H; Andersson, AT; Jespers, W; Ghahremanpour, MM; van der Spoel, D or concate me.. Category: ethers-buliding-blocks

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Ether – Wikipedia,
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Recently I am researching about MEDIUM-RANGE STRUCTURE; HYDROTHERMAL CONVERSION; NANOSIZED ZEOLITES; CATALYTIC-ACTIVITY; EXTERNAL SURFACE; BETA; NANOZEOLITES; MECHANISM; EFFICIENT; INSIGHT, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21902154]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Xu, LJ; Yuan, YY; Han, Q; Dong, L; Chen, L; Zhang, XM; Xu, L. The CAS is 103-50-4. Through research, I have a further understanding and discovery of Benzyl ether. Recommanded Product: 103-50-4

A novel interzeolite transformation strategy using internally confined organic structure directing agents (OSDAs), called the OSDA-confined strategy, is proposed for highly crystalline nanosized high-silica ZSM-5 zeolite synthesis, by which high yield and fast synthesis of ZSM-5 is achieved using BEA zeolite as a raw material. The transformation process was investigated by XRD, SEM, ICP, FTIR and UV Raman spectroscopy, which revealed that the decomposition of a parent zeolite and the crystallization process of products were well modulated by the confined OSDA. The transformation process could be divided into three stages consisting of raw material deconstruction, small size product formation and product growth. The strong etching power of NaOH contributes to the fast decomposition of BEA zeolites. In addition, tetrapropylammonium hydroxide (TPAOH) as an OSDA was confined in the parent zeolite instead of being added into the mother liquid, achieving a high local concentration of TPAOH, which could reduce the decomposition rate of the parent BEA zeolite and promote the efficient organization of the building units generated by the decomposition of the BEA zeolite. Thereof, a high yield was achieved by the synergistic effect of NaOH and occluded TPAOH. During the interzeolite transformation process, the six-membered rings (6Rs), five-membered rings (5Rs) and four-membered rings (4Rs) in the BEA zeolite framework were disassembled and combined with the help of 5Rs to produce the ZSM-5 zeolite structure. Moreover, due to the nanoscale and large surface area, the obtained ZSM-5 zeolite catalyst showed extremely high catalytic activity in the self-etherification reaction of benzyl alcohol (BA) to dibenzyl ether (DE). This study provides insights into the interzeolite transformation process, which would be helpful for achieving size control and high-efficiency synthesis.

Recommanded Product: 103-50-4. About Benzyl ether, If you have any questions, you can contact Xu, LJ; Yuan, YY; Han, Q; Dong, L; Chen, L; Zhang, XM; Xu, L or concate me.

Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

In 2019 LANGMUIR published article about SULFONATED COPOLYMERS; SIZE; TEMPERATURES; STABILITY; BRINE in [Yu, Jin; Wong, Joyce Y.] Boston Univ, Div Mat Sci & Engn, Boston, MA 02215 USA; [Nap, Rikkert J.; Szleifer, Igal] Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA; [Nap, Rikkert J.; Szleifer, Igal] Northwestern Univ, Chem Life Proc Inst, Evanston, IL 60208 USA; [Wong, Joyce Y.] Boston Univ, Dept Biomed Engn, Boston, MA 02215 USA in 2019, Cited 23. The Name is Benzyl ether. Through research, I have a further understanding and discovery of 103-50-4. Computed Properties of C14H14O

Superparamagnetic nanoparticles (SPIONs) can be used as nuclear magnetic resonance (NMR) signal enhancement agents for petroleum exploration. This enhancement effect is uniform if SPIONs are monodisperse in size and in composition; yet it is challenging to synthesize mono disperse particles that do not aggregate in high salinity petroleum brine. Here, we report a method to synthesize individual SPIONs coated with tunable surface coating densities of poly(2-acrylamido-2-methyl-1-propanesulfonic acid (pAMPS) with a catechol end-group (pAMPS*). To establish parameters under which pAMPS*-coated SPIONS do not aggregate, we compared computational predictions with experimental results for variations in pAMPS* chain length and surface coverage. Using this combined theoretical and experimental approach, we show that singly dispersed SPIONs remained stabilized in petroleum brine for up to 75 h with high surface density pAMPS*.

About Benzyl ether, If you have any questions, you can contact Yu, J; Nap, RJ; Szleifer, I; Wong, JY or concate me.. Computed Properties of C14H14O

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Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

Recently I am researching about ENCAPSULATED GAMMA-FE2O3 NANOPARTICLES; SINGLE-SOURCE PRECURSORS; N-HETEROCYCLIC CARBENES; ARYL CHLORIDES; EFFICIENT CATALYST; HETEROGENEOUS CATALYST; TRANSFER HYDROGENATION; ORGANIC-REACTIONS; CARBON-CARBON; PALLADIUM(II) COMPLEXES, Saw an article supported by the Council of Scientific and Industrial Research (CSIR), New Delhi, IndiaCouncil of Scientific & Industrial Research (CSIR) – India; University Grants Commission (India)University Grants Commission, India. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Sharma, AK; Joshi, H; Singh, AK. The CAS is 101-84-8. Through research, I have a further understanding and discovery of Diphenyl oxide. Computed Properties of C12H10O

Nanoparticles layered with palladium(0) were prepared from nano-sized magnetic Fe3O4 by coating it with silica and then reacting sequentially with phenylselenyl chloride under an N-2 atmosphere and palladium(ii) chloride in water. The resulting Fe3O4@SiO2@SePh@Pd(0) NPs are magnetically retrievable and the first example of NPs in which the outermost layer of Pd(0) is mainly held by selenium. The weight percentage of Pd in the NPs was found to be 1.96 by ICP-AES. The NPs were authenticated via TEM, SEM-EDX, XPS, and powder XRD and found to be efficient as catalysts for the C-O and C-C (Suzuki-Miyaura) coupling reactions of ArBr/Cl in water. The oxidation state of Pd in the NPs having size distribution from similar to 12 to 18 nm was inferred as zero by XPS. They can be recycled more than seven times. The main features of the proposed protocols are their mild reaction conditions, simplicity, and efficiency as the catalyst can be separated easily from the reaction mixture by an external magnet and reused for a new reaction cycle. The optimum loading (in mol% of Pd) was found to be 0.1-1.0 and 0.01-1.0 for O-arylation and Suzuki-Miyaura coupling, respectively. For ArCl, the required amount of NPs was more as compared to that needed for ArBr. The nature of catalysis is largely heterogeneous.

Computed Properties of C12H10O. About Diphenyl oxide, If you have any questions, you can contact Sharma, AK; Joshi, H; Singh, AK or concate me.

Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

An article Organophosphate flame retardants and plasticizers in sediment and bivalves along the Korean coast: Occurrence, geographical distribution, and a potential for bioaccumulation WOS:000539160000055 published article about POLYBROMINATED DIPHENYL ETHERS; SPATIAL-DISTRIBUTION; INDUSTRIALIZED BAYS; MARINE-SEDIMENTS; TEMPORAL TRENDS; LAKE SHIHWA; CONTAMINATION; WATER; PBDES; OPFRS in [Choi, Woosik; Lee, Sunggyu; Lee, Hyun-Kyung; Moon, Hyo-Bang] Hanyang Univ, Coll Sci & Technol, Dept Marine Sci & Convergent Technol, Ansan 426791, South Korea in 2020.0, Cited 44.0. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8. Product Details of 101-84-8

Environmental contamination by organophosphate flame retardants (OPFRs) and plasticizers are environmental concerns. In this study, 18 OPFRs were analyzed in sediment and bivalves collected from 50 locations along the Korean coast to assess occurrence, geographical distribution, contamination source, and bioaccumulation potential. Tris(1-chloro-2-propanyl) phosphate (TCPP) and tris(2-ethylhexyl) phosphate (TEHP) were highly detected (> 80%) OPFRs in sediment and bivalves. Total concentrations of OPFRs and plasticizers in sediment and bivalves ranged from 2.18 to 347 ng/g dry weight and from 6.12 to 206 ng/g dry weight, respectively, which were within the ranges reported for previous studies. Sedimentary organic carbon was a primary factor governing the OPFR distribution. Concentrations of OPFRs and plasticizers in sediments from harbor zones were significantly higher than non-harbor zones, indicating that shipping activity is a contamination source of OPFRs and plasticizers in coastal environments. Biota-sediment accumulation factors < 1 for several OPFRs indicated limited potential for bioaccumulation. About Diphenyl oxide, If you have any questions, you can contact Choi, W; Lee, S; Lee, HK; Moon, HB or concate me.. Product Details of 101-84-8

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Recommanded Product: 101-84-8. I found the field of Materials Science very interesting. Saw the article Preparation and characterization of lanthanum nitrate nanoparticles by a polyol method published in 2019.0, Reprint Addresses Estrada-de la Vega, A (corresponding author), ITESM, Dept Ingn Mecan, Tecnol, Av Eugenio Garza Sada 2501 Sur, Monterrey 64849, NL, Mexico.. The CAS is 101-84-8. Through research, I have a further understanding and discovery of Diphenyl oxide.

We present the synthesis of lanthanum nitrate nanoparticles via the polyol method. A crystallographic study of La(NO3)(3)center dot 4H(2)O nanoparticles was carried out using the Rietveld method and XRD to detect the phases of the yield: alpha (monoclinic) and beta (orthorhombic) phases were obtained. Thermogravimetric analysis showed a unique dehydration process in the 65 degrees C-245 degrees C temperature range and a dehydroxylation phase in the 333 degrees C-558 degrees C temperature range. Using TEM-EDX, and DLS, the purity of the material was evaluated; a spherical shape morphology and monodispersity were observed. The absorbance at 1340-1440 cm(-1) and 1500-1600 cm(-1) (IR regions) of the lanthanum nanoparticles was deconvolved to increase the resolution of the chemical imprint in these regions.

About Diphenyl oxide, If you have any questions, you can contact Estrada-de la Vega, A; Bedoya-Calle, AH; Diabb, J; Villarreal-Rios, AL; Elias-Zuniga, A; Lopez-Cuellar, EM; Ortiz-Mendez, AU or concate me.. Recommanded Product: 101-84-8

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,Ether | (C2H5)2O – PubChem

An article Debromination of polybrominated diphenyl ethers (PBDEs) by palladized zerovalent zinc particles: Influence factors, pathways and mechanism WOS:000536175700092 published article about BROMINATED FLAME RETARDANTS; REDUCTIVE DEBROMINATION; DECHLORINATION; KINETICS; SOIL; BIODEGRADATION; DEGRADATION; CORROSION; EXPOSURE; SYSTEMS in [Xu, Yongye; Liang, Chenghao; Zhang, Taiping; Wang, Rui; Huang, Kaibo; Dang, Zhi; Yin, Hua; Lu, Guining] South China Univ Technol, Sch Environm & Energy, Guangzhou 510006, Peoples R China; [Zhang, Taiping; Dang, Zhi; Yin, Hua; Lu, Guining] Minist Educ, Key Lab Pollut Control & Ecosyst Restorat Ind Clu, Guangzhou 510006, Peoples R China; [Tao, Xueqin; Pan, Zhaoxi] Zhongkai Univ Agr & Engn, Sch Environm Sci & Engn, Guangzhou 510225, Peoples R China in 2020.0, Cited 40.0. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8. SDS of cas: 101-84-8

We synthesized a novel material, namely palladized zero-valent zinc (Pd/ZVZ), and investigated its efficiency for the degradation of polybrominated diphenyl ethers (PBDEs). The plated Pd significantly enhances the degradation rate of PBDEs by ZVZ at the optimum loading of 1% by weight. In the Pd/ZVZ system, very few lower BDEs were accumulated during the degradation of 2,2′,4,4′- tetrabromodiphenyl ether (BDE-47) and the final product is diphenyl ether, whereas the ZVZ system only debrominates BDE-47 to di-BDE and further debromination becomes very difficult. The degradation rates of BDEs by ZVZ greatly decreased with decreased bromination level, while in Pd/ZVZ system, the degradation rates of PBDEs did not show a significant difference. These indicate different mechanisms. This was confirmed by investigating the debromination pathways of the PBDEs in both systems. We determined that a H-transfer was the dominant mechanism in the Pd/ZVZ system. In addition, the reactivity of Pd/ZVZ to BDE-47 is pH-independent, which has a great advantage for various applications over ZVZ alone. Our study provides a new approach for the remediation of the PBDEs pollution. (C) 2020 Elsevier Ltd. All rights reserved.

SDS of cas: 101-84-8. About Diphenyl oxide, If you have any questions, you can contact Xu, YY; Liang, CH; Zhang, TP; Tao, XQ; Wang, R; Huang, KB; Pan, ZX; Dang, Z; Yin, H; Lu, GN or concate me.

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Ether – Wikipedia,
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COA of Formula: C14H14O. In 2021 J CROHNS COLITIS published article about CROHNS-DISEASE; BIRTH OUTCOMES; ULCERATIVE-COLITIS; PRETERM BIRTH; ALPHA; RISK; EXPRESSION; MANAGEMENT; FERTILITY; RECEPTORS in [Kim, Min-A] Yonsei Univ, Gangnam Severance Hosp, Inst Womens Life Med Sci, Dept Obstet & Gynecol,Coll Med, Seoul, South Korea; [Kim, Young-Han] Yonsei Univ, Severance Hosp, Inst Womens Life Med Sci, Dept Obstet & Gynecol,Coll Med, Seoul, South Korea; [Chun, Jaeyoung] Yonsei Univ, Gangnam Severance Hosp, Dept Internal Med, Coll Med, Seoul, South Korea; [Lee, Hye Sun] Yonsei Univ, Biostat Collaborat Unit, Coll Med, Seoul, South Korea; [Park, Soo Jung; Cheon, Jae Hee; Il Kim, Tae; Kim, Won Ho; Park, Jae Jun] Yonsei Univ, Severance Hosp, Dept Internal Med, Coll Med, Seoul, South Korea in 2021, Cited 65. The Name is Benzyl ether. Through research, I have a further understanding and discovery of 103-50-4.

Background and Aims: Robust evidence regarding the impact of disease activity on pregnancy outcomes in women with inflammatory bowel disease [IBD] is crucial for both clinicians and patients in preparing a birth plan. We sought to perform a systematic review and meta-analysis to assess the pooled influences of disease activity on pregnancy outcomes in women with IBD. Methods: We searched MEDLINE, EMBASE and the COCHRANE library to identify articles comparing pregnancy outcomes between active and inactive IBD at the time of conception or during pregnancy. A meta-analysis was performed using a random-effects model to pool estimates and report odds ratios [ORs]. Results: A total of 28 studies were identified as eligible for the meta-analysis. In women with active IBD, the pooled ORs for low birth weight [LBW], preterm birth, small for gestational age [SGA], spontaneous abortion and stillbirths were respectively 3.81 (95% confidence interval [CI] 1.81-8.02), 2.42 [95% CI 1.74-3.35], 1.48 [95% CI 1.19-1.85], 1.87 [95% CI 1.17-3.0] and 2.27 [95% CI 1.03-5.04] compared to women with inactive IBD. In the subgroup analysis based on disease type, women with active ulcerative colitis had an increased risk of LBW, preterm birth and spontaneous abortion. Women with active Crohn’s disease had a higher risk of preterm birth, SGA and spontaneous abortion. Conclusions: Active IBD during the periconception period and pregnancy is associated with an increased risk of adverse pregnancy outcomes. Our data suggest that pregnancy should be planned when the disease is quiescent, and continuous disease control is important even during pregnancy.

COA of Formula: C14H14O. About Benzyl ether, If you have any questions, you can contact Kim, MA; Kim, YH; Chun, J; Lee, HS; Park, SJ; Cheon, JH; Il Kim, T; Kim, WH; Park, JJ or concate me.

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,Ether | (C2H5)2O – PubChem

Computed Properties of C14H14O. Staniuk, M; Rechberger, F; Tervoort, E; Niederberger, M in [Staniuk, Malwina; Rechberger, Felix; Tervoort, Elena; Niederberger, Markus] Swiss Fed Inst Technol, Dept Mat, Lab Multifunct Mat, Vladimir Prelog Weg 5, CH-8093 Zurich, Switzerland published Adapting the concepts of nonaqueous sol-gel chemistry to metals: synthesis and formation mechanism of palladium and palladium-copper nanoparticles in benzyl alcohol in 2020, Cited 58. The Name is Benzyl ether. Through research, I have a further understanding and discovery of 103-50-4.

Benzyl alcohol is a versatile reaction medium for the synthesis of different types of nanoparticles. Its ability to act as an oxygen source gave access to metal oxide nanoparticles, while its reducing properties can be harnessed for the preparation of metals. Here we report the synthesis of Pd and PdCu nanoparticles in benzyl alcohol supplemented by a detailed mechanistic study for both systems. To elucidate the chemical formation mechanism of the Pd nanoparticles, we performed in situ attenuated total reflection ultraviolet-visible (ATR-UV-vis) and Fourier transform infrared spectroscopy (ATR-FTIR), providing information on the organic as well as on the inorganic side of the reaction. Potential gaseous products were analyzed by in situ gas chromatography (GC) and mass spectrometry (MS). We observed the formation of benzaldehyde, toluene, and dibenzyl ether as the three main organic products. The formation of the PdCu alloy nanoparticles was studied by ex situ powder X-ray diffraction (PXRD). A time-resolved study of the synthesis at 100 degrees C indicated that initially three types of particles formed, composed of an alloy with high Pd content, an alloy with high content of copper, and palladium particles, and only later in the reaction course they transformed into an alloy with a Pd-to-Cu ratio close to 1. [GRAPHICS] .

Computed Properties of C14H14O. About Benzyl ether, If you have any questions, you can contact Staniuk, M; Rechberger, F; Tervoort, E; Niederberger, M or concate me.

Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem