Application In Synthesis of Diphenyl oxide. Authors Wang, Q; Xiao, J; Su, YH; Huang, JW; Li, JH; Qiu, LG; Zhan, MX; He, X; Yuan, WZ; Li, Y in ROYAL SOC CHEMISTRY published article about in [Wang, Qian; Xiao, Jing; Su, Yanhong; Huang, Jianwen; Li, Jihua; Qiu, Lige; Zhan, Meixiao; He, Xu; Li, Yong] Jinan Univ, Zhuhai Hosp, Zhuhai Peoples Hosp, Zhuhai Intervent Med Ctr,Zhuhai Precis Med Ctr, Zhuhai 519000, Guangdong, Peoples R China; [Wang, Qian; Yuan, Weizhong] Tongji Univ, Sch Mat Sci & Engn, Shanghai 201804, Peoples R China in 2021.0, Cited 58.0. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8
Amphiphilic thermoresponsive block helical poly(phenyl isocyanide) was synthesized by the polymerization of phenyl isocyanide using a Pd(ii) complex catalyst as an initiator. The polymer could self-assemble into spherical micelles. The lower critical solution temperature (LCST) of the micelle solution was adjusted by changing the molar ratio of the hydrophobic segment to the hydrophilic segment and finally optimized to be 41 degrees C at a molar ratio of 1 : 2. After loading Fe3O4 nanoparticles, the magnetic complex micelles were prepared. The magnetic complex micelles demonstrated reversible thermoresponsiveness and obvious magnetic hyperthermia. Cell viability measurements indicated that the nanomaterials were well-biocompatible and nontoxic. The magnetic complex micelles could be used as nanocarriers to achieve controlled release of doxorubicin (DOX) by altering the temperature. Intracellular experiments demonstrated that the magnetic complex micelles showed excellent anticancer synergistic thermo-chemotherapy performance under an alternating magnetic field (AMF) owing to magnetic hyperthermia from micelle-loaded Fe3O4 nanoparticles and effective drug release due to the morphology change of thermoresponsive poly(phenyl isocyanide)s.
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