Recommanded Product: Benzyl ether. Amirshaghaghi, A; Yan, L; Miller, J; Daniel, Y; Stein, JM; Busch, TM; Cheng, ZL; Tsourkas, A in [Amirshaghaghi, Ahmad; Yan, Lesan; Stein, Joel M.; Cheng, Zhiliang; Tsourkas, Andrew] Univ Penn, Dept Bioengn, Philadelphia, PA 19104 USA; [Miller, Joann; Busch, Theresa M.] Univ Penn, Perelman Sch Med, Dept Radiat Oncol, Philadelphia, PA 19104 USA; [Daniel, Yonathan] Univ Maryland, Dept Biol, Coll Comp Math & Nat Sci, College Pk, MD 20742 USA; [Stein, Joel M.] Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA published Chlorin e6-Coated Superparamagnetic Iron Oxide Nanoparticle (SPION) Nanoclusters as a Theranostic Agent for Dual Mode Imaging and Photodynamic Therapy in 2019, Cited 49. The Name is Benzyl ether. Through research, I have a further understanding and discovery of 103-50-4.
Photodynamic therapy (PDT) is an approved modality for the treatment of various types of maligancies and diseased states. However, most of the available photosensitizers (PS) are highly hydrophobic, which limits their solubility and dispersion in biological fluids and can lead to self-quenching and sub-optimal therapeutic efficacy. In this study, chlorin e6 (Ce6)-coated superparamagnetic iron oxide nanoparticle (SPION) nanoclusters (Ce6-SCs) were prepared via an oil-in-water emulsion. The physical chemical properties of the Ce6-SCs were systematically evaluated. Dual-mode imaging and PDT was subsequently performed in tumor-bearing mice. Chlorin e6 is capable of solubilizing hydrophobic SPION into stable, water-soluble nanoclusters without the use of any additional amphiphiles or carriers. The method is reproducible and the Ce6-SCs are highly stable under physiological conditions. The Ce6-SCs have an average diameter of 92 nm and low polydispersity (average PDI < 0.2). Encapsulation efficiency of both Ce6 and SPION is approximate to 100%, and the total Ce6 payload can be as high as 56% of the total weight (Ce6 + Fe). The Ce6-SCs localize within tumors via enhanced permeability and retention and are detectable by magnetic resonance (MR) and optical imaging. With PDT, Ce6-SCs demonstrate high singlet oxygen generation and produce a significant delay in tumor growth in mice. Recommanded Product: Benzyl ether. About Benzyl ether, If you have any questions, you can contact Amirshaghaghi, A; Yan, L; Miller, J; Daniel, Y; Stein, JM; Busch, TM; Cheng, ZL; Tsourkas, A or concate me.
Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem