Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2398-37-0, name is 1-Bromo-3-methoxybenzene, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 1-Bromo-3-methoxybenzene
Acetyl chloride (3.56 mL, 0.06 mol) is added dropwise to a stirred suspension of 3-bromoanisole (9.35 g, 0.05 mol) and AlCl3 (8.00 g, 0.06 mol) in dichloromethane (50 mL) at 0 C under argon. The resulting mixture is stirred at 0 0C for 40 min and then at room temperature for 1 h, and diluted with H2O (100 mL) and 2 N HCl (35 mL), and extracted with ethyl acetate (2 x 100 mL and 50 mL). The extract is washed (brine) and dried. After solvent removal at reduced pressure, the residue is purified on silica gel (12.5% to 14.3% ethyl acetate/hexane) to give 9.55 g (83%) of 2 as a colorless liquid. IR 2964, 1688, 1596, 1252 cm”1; 1H NMR (CDCI3) delta 2.66 (s, 3H, CH3CO), 3.88 (s, 3H, CH3O), 6.91 (dd, J= 8.4 Hz, 2.4 Hz, IH, 5-PhH), 7.19 (d, J= 2.4 Hz, IH, 3- PhH), 7.63 ppm (d, J= 8.4 Hz, IH, 6-PhH).
According to the analysis of related databases, 2398-37-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BURNHAM INSTITUTE FOR MEDICAL RESEARCH; MERCOLA, Mark; DAWSON, Marcia, I.; CASHMAN, John; WO2010/33643; (2010); A2;,
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