Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 89282-70-2, name is 2-Methoxy-2-methylpropan-1-amine, This compound has unique chemical properties. The synthetic route is as follows., Formula: C5H13NO
A mixture of phenyl 5-({trans-4-[(2-chloro-4,5-difluorophenyl)carbamoyl]cyclohexyl}carbamoyl)-1 H-im idazole-4-carboxylate (100 mg, 0.199 mmol,) and 2-methoxy-2-methylpropan-1 -amine (103 mg, 0.994 mmol, GAS No 89282-70-2) in tetrahydrofuran (5.0 ml) was stirred at 600 ove r night. For work-up, the reaction mixture was concentrated and the residue was first purified by flash chromatography (10 g Snap Gartridge, ethyl acetate/ethanol gradient, 0% -> 5% ethanol) followd by purification withpreparative HPLG (Method 9) to yield the title compound (46.0 mg, 45% yield).LG-MS (Method 3): R = 1.15 mm; MS (ESIpos) m/z = 512.2 [M+H].1HNMR (400 MHz, DMSO-d6): 6 [ppm] = 13.38-13.09 (m, 1H), 11.25-1 0.90 (m, 1H), 9.67-9.53 (m, 1H), 8.52-8.25 (m, 0.5H), 8.21-7.95 (m, 0.5H), 7.87-7.75 (m, 3H), 3.92-3.59 (m, 1H),3.37 (d, 2H), 3.15 (5, 3H), 2.15-1.77 (m, 4H), 1.65-1.20 (m, 4H), 1.14 (5, 6H).
According to the analysis of related databases, 89282-70-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; EIS, Knut; ACKERMANN, Jens; WAGNER, Sarah; BUCHGRABER, Philipp; SUeLZLE, Detlev; HOLTON, Simon; BENDER, Eckhard; LI, Volkhart; LIU, Ningshu; SIEGEL, Franziska; LIENAU, Philip; BAIRLEIN, Michaela; VON NUSSBAUM, Franz; HERBERT,Simon; KOPPITZ, Marcus; (734 pag.)WO2016/177658; (2016); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem