Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 162705-07-9, name is (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)aniline, A new synthetic method of this compound is introduced below., Recommanded Product: (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)aniline
Example 8 (Z)-1-(3-hydroxy-4-methoxyphenyl)-3-((2-methoxy-5-((Z)-3,4,5-trimethoxystyryl)phenyl)amino) prop-2-en-1-one (10q) To a stirred solution of (Z)-2-methoxy-5-(3,4,5-trimethoxystyryl)aniline (5d) (100 mg, 0.317 mmol) in ethanol (5 ml) 1-(3-hydroxy-4-methoxyphenyl)prop-2-yn-1-one (6q) (55.85 mg, 0.317 mmol) was added. The reaction mixture was stirred at a temperature of 24 C. for 4 h and the reaction was monitored by TLC using hexane/ethyl acetate (6:4) as a solvent system. Then appropriate water was added to reaction mixture. A yellow colour solid appears which was filtered and washed with ethanol. (yield: 110 mg, 70%); mp: 88-91 C.; 1H NMR (CDCl3, 300 MHz) deltadelta (ppm): 3.71 (s, 6H), 3.85 (s, 3H), 3.94 (s, 6H), 5.68 (s, 1H), 5.91 (d, J=8.3 Hz, 1H), 6.49 (d, J=13.6 Hz, 4H), 6.79 (d, J=8.3 Hz, 1H), 6.96-6.87 (m, 2H), 7.12 (s, 1H), 7.24-7.18 (m, 1H), 7.50 (d, J=6.7 Hz, 2H), 12.06 (d, J=12.1 Hz, NH); FABMAS:(M+H)=478.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Council of Scientific and Industrial Research; Ahmed, Kamal; Gajjela, Bharath Kumar; Anver, Basha Shaik; Vangala, Santhosh Reddy; Mahesh, Rasala; US2015/322009; (2015); A1;,
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