In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 768-70-7 as follows. Application In Synthesis of 3-Ethynylanisole
1.0 mmol of m-methoxyphenylacetylene, 1.5 mol of sodium azide, 1.2 mmol of benzyl bromide, and 0.1 mmol of cuprous iodide were added to 4002.0 mL of polyethylene glycol, and the reaction was stirred at room temperature for 35 minutes, and the reaction was completed. The product was treated by column chromatography V petroleum ether: V ethyl acetate = 3: 1 to obtain 1-benzyl-4- (3-methoxy) phenyl1,2,3-triazole. The product was a white solid. Yield: 92%.
According to the analysis of related databases, 768-70-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Leshan Normal University; Zeng Hongyao; Xia Liewen; Wang Yinghong; (13 pag.)CN110498772; (2019); A;,
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