A new synthetic route of Diphenyl oxide

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Diphenyl oxide, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 101-84-8, name is Diphenyl oxide, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 101-84-8, Formula: C12H10O

EXAMPLE 1; A reactor is configured from a 1-liter Morton flask with a mechanical stirrer, thermometer, a 60 mL addition funnel, and a distillation column. The condenser from the distillation column is connected to a H2O trap. A small N2 purge is added to the line from the condenser to the H2O trap. The reactor is charged with AlCl3 and bromine. The addition funnel is charged with diphenyl oxide. The reactor is heated to 55 C. and the diphenyl oxide is added drop-wise supersurface to the bromine. The reactor is heated by a mantle. After all of the diphenyl oxide has been added, the addition funnel is replaced with a Br2 feed line. After several minutes of refluxing, the distillation of Br2 (containing HBr) is initiated. At the same time, the Br2 feed is initiated. As needed, the feed rate of the Br2 is adjusted so that the volume in the reactor remains fairly constant. After the distillation and concurrent replacement feed of Br2 are conducted for an hour, the liquid mixture is cooled to 55 C., some deionized H2O is added, and most of the Br2 is distilled off. When most of the Br2 is gone, more deionized water is added. The remaining Br2 is then distilled. The remaining mixture is cooled to 60 C., and a portion of an aqueous 25% NaOH solution is added to make the pH 13-14. The resultant mixture is filtered and washed well with deionized water. A sample is subjected to GC analysis and then is oven dried.

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Diphenyl oxide, and friends who are interested can also refer to it.

Reference:
Patent; ALBEMARLE CORPORATION; US2008/58558; (2008); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem