Electric Literature of 79128-08-8,Some common heterocyclic compound, 79128-08-8, name is 1,3-Diisopropoxybenzene, molecular formula is C12H18O2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
at 0 adding n-butyllithium (2.5M, 40mL, 100mmol) in hexane solution was added to the compoundIt was 2 (19.4g, 100mmol) in THF (10 mL), and the mixture was stirred at 15 2 hours.After the mixture was cooled to 0 again, iodine (25.4g, 100mmol) were added thereto, and 10 The mixture was stirred for 16 hours. Saturated aqueous solution of sodium sulfite (50 mL) was added to the reaction solution toThe reaction was quenched, and the organic solvent was removed under reduced pressure. Thereafter, ethyl acetate (50mL × 3) extraction residue.The organic layer was dehydrated over sodium sulfate and concentrated. By using petroleum ether as eluent, concentrate purified by silica gel columnThereof, whereby the compound 3.
The synthetic route of 79128-08-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Japan Polypropylene Corporation; Tanna, Akirahisashi; Sato, Naomasa; Konishi, Yohei; Oishi, Yasuo; (27 pag.)CN105593235; (2016); A;,
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