Related Products of 16452-01-0, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 16452-01-0 as follows.
(a) 4-methyl-3-methoxy aniline, (7.6 g, 50 mmol) 6 ml acetic acid and 6 ml acetic anhydride were combined which produced an exotherm. The mixture was cooled to ambient temperature. Concentrated nitric acid (15 ml) which had been cooled in an ice bath was added. The mixture crystallized and was treated liberally with water to yield 7.8 g of 2-nitro-4-methyl-5-methoxy acetanilide solids.
According to the analysis of related databases, 16452-01-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Zeneca Limited; US5369086; (1994); A;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem