Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 707-07-3, name is (Trimethoxymethyl)benzene, A new synthetic method of this compound is introduced below., HPLC of Formula: C10H14O3
To a suspension of known p-tolyl 2-O-benzyl-1-thio-beta-L-fucopyranoside 2 (3.5 g, 9.7 mmol) in dry CH3CN (20 mL), trimethyl orthobenzoate (2.2 mL, 12.6 mmol) was added followed by the addition of CSA (25 mg). The reaction mixture was allowed to stir at room temperature for 2 h until the TLC (n-hexane-EtOAc; 2:1) showed complete conversion of the starting material. Then the solvents were evaporated in vacuo and the crude mixture was diluted with CH2Cl2 (25 mL) and washed with 1 M HCl (2 25 mL). The organic layer was then collected, dried (Na2SO4) and filtered. The solvents were then evaporated and the crude mixture was purified by flash chromatography to give the pure product 3 (3.9 g, 87%) asa colourless syrup.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Das, Rituparna; Mahanti, Mukul; Mukhopadhyay, Balaram; Carbohydrate Research; vol. 399; (2014); p. 15 – 20;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem