Electric Literature of 1758-46-9, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1758-46-9, name is 2-Phenoxyethylamine, This compound has unique chemical properties. The synthetic route is as follows.
A mixture of intermediate compound (prepared ac- cording to teachings in WO99/58530 of which the content is included herein) (0.025 mol) and 2-phenoxyethanamine (0.036 mol) in THF (300 ml) was hydrogenated at 140 °C for 16 hours with Pd/C 10 percent (3 g) as a catalyst in the presence of thiophene solution (3ml). After uptake of H2 (1 equivalent), the catalyst was filtered off and the filtrate was evaporated. The residue was triturated in 2-propanol. The precipitate was filtered off and dried. Yielding: 12.4 g of final compound 7 (94 percent).
The chemical industry reduces the impact on the environment during synthesis 2-Phenoxyethylamine. I believe this compound will play a more active role in future production and life.
Reference:
Patent; JANSSEN PHARMACEUTICA N.V.; WO2006/67139; (2006); A1;,
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