Synthetic Route of 74654-07-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 74654-07-2 name is 2-(2-(2-Methoxyethoxy)ethoxy)ethanamine, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Step a):Under inert atmosphere,5.00 g of 4-bromo-1,8-naphthalic anhydride was added to 100 mL of anhydrous methanol,1.96 g of 3,6,9-trioxa-1-aminodecane was further injected, and the mixture was refluxed for 10 hours.After the reaction was completed, overnight needle-like crystals were precipitated, filtered, washed with cold ethanol three times,The intermediate N-3,6,9-trioxadecyl-4-bromo-1,8-naphthalimide was obtained4.90 g (96% yield).
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2-(2-(2-Methoxyethoxy)ethoxy)ethanamine, and friends who are interested can also refer to it.
Reference:
Patent; Zhejiang Sci-Tech University; Han Yifeng; Chen Bo; Wei Ting; (13 pag.)CN105542756; (2017); B;,
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