Adding a certain compound to certain chemical reactions, such as: 82172-73-4, name is O-(2-Methoxyethyl)hydroxylamine hydrochloride, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 82172-73-4, Formula: C3H10ClNO2
General procedure: To a solution of bis(4-hydroxy)benzophenone (100 mg, 0.46 mmol) in EtOH (2 mL) was added hydroxylamine HCl (69 mg, 0.99 mmol) at ambient temperature. The reaction mixture was stirred until complete consumption of the starting material on TLC and quenched with H2O. The resulting mixture was diluted with EtOAc, and the organic phase was washed with H2O and brine, dried over MgSO4 and concentrated in vacuo Purification of the residue via flash column chromatography on silica gel (EtOAc : Hexane = 1 : 5 to 1 : 3) afforded 90 mg (84 %) of 12a as colorless liquid.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, O-(2-Methoxyethyl)hydroxylamine hydrochloride, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Kim, Taelim; Kim, Hye-In; An, Ji-Young; Lee, Jun; Lee, Na-Rae; Heo, Jinyuk; Kim, Ji-Eun; Yu, Jihyun; Lee, Yong Sup; Inn, Kyung-Soo; Kim, Nam-Jung; Bioorganic and Medicinal Chemistry Letters; vol. 26; 7; (2016); p. 1844 – 1848;,
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