Continuously updated synthesis method about C6H15NO2

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 645-36-3.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 645-36-3, name is 2,2-Diethoxyethanamine, This compound has unique chemical properties. The synthetic route is as follows., Safety of 2,2-Diethoxyethanamine

2,2-Diethoxyethylamine (3.35 mL, 23 mmol) and Et3N (3.2 mL, 23mmol) were added to a suspension of pyrimidine 818 (3.0 g, 15.4mmol) in i-PrOH (50 mL), and the mixture was heated in the sandbath at 60-65 C for 3 h. H2O (200 mL) was added and the precipitate was collected by filtration, dried, and crystallized (hexane) to give a colorless solid; yield: 4.05 g (90%); mp 76-77 C.IR (KBr): 3324 (NH) cm-1.1H NMR (300 MHz, CDCl3): delta = 1.26 (t, J = 6.9 Hz, 6 H, 2 × CH3),2.53 (s, 3 H, SCH3), 3.45-3.64 (m, 4 H, NCH2 and 2 × CHAHBCH3),3.75 (dq, 2J = 9.6 Hz, 3J = 6.9 Hz, 2 H, 2 × CHAHBCH3), 4.62 (t,J = 5.1 Hz, 1 H, OCH), 5.21 (br s, 1 H, NH), 6.11 (s, 1 H, Ar-H).13C NMR (75 MHz, DMSO-d6): delta = 14.1, 16.0, 43.5, 62.5, 99.9,100.5, 157.3, 163.3, 171.9.Anal. Calcd for C11H18ClN3O2S: C, 45.28; H, 6.22. Found: C,45.48; H, 6.52.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 645-36-3.

Reference:
Article; Juskenas, Robertas; Masevicius, Viktoras; Tumkevicius, Sigitas; Synthesis; vol. 45; 17; (2013); p. 2438 – 2446;,
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