Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 104566-41-8, name is (3-(Benzyloxy)phenyl)methanamine hydrochloride, This compound has unique chemical properties. The synthetic route is as follows., category: ethers-buliding-blocks
EXAMPLE 1A 4-Chloro-5-(3-benzyloxybenzylamino)-2-i-propyl-3-(2H)pyridazinone (Compound No. 95) STR61 A mixture comprising 8.24 g of 3-benzyloxybenzylamine hydrochloride prepared in Reference Example 2A, 3.11 g of 2-i-propyl-4,5-dichloro-3(2H)pyridazinone, 7.26 g of potassium carbonate, 30 ml of 1,4-dioxane and 90 ml of water was refluxed under stirring for 4.5 hours. The majority of 1,4-dioxane was distilled off under reduced pressure, and the residue was extracted with ethyl acetate. The extract was washed with diluted hydrochloric acid, and then treated with cerite to remove the precipitate. The organic layer was separated, and washed with water and a saturated sodium chloride aqueous solution, and then dried over sodium sulfate. Then, the solvent was distilled off. The pale yellow oily substance thereby obtained was crystallized from ether-n-hexane to obtain 2.51 g of the above identified compound having a melting point of from 106 to 108 C. as colorless crystals. NMR(CDCl3)6: 7.48 (1H, s), 7.30 (5H, s), 7.3-6.7 (4H, m), 5.02 (2H, s), 4.49, 4.40 (total 2H, each s), 5.2-4.8 (1H, broad s), 1.30 (6H, d). MS (m/e): 383(M+), 348, 91 (100%).
According to the analysis of related databases, 104566-41-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Nissan Chemical Industries Ltd.; US5098900; (1992); A;,
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