Reference of 10075-63-5,Some common heterocyclic compound, 10075-63-5, name is 1,5-Dimethoxynaphthalene, molecular formula is C12H12O2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
9.5 g of Intermediate 1-1 was dissolved in 150 ml of acetonitrile, and 8.9 g of N-bromosuccinimide was slowly dropwise added thereto at 0 C. for 10 minutes. The reaction mixture was slowly heated from 0 C. to ambient temperature for 4 hours, and the reaction was terminated by adding water. The reaction mixture was distilled under a reduced pressure, and the residue was subjected to extraction three times using ethyl acetate. The resultant was dried using anhydrous magnesium sulfate and distilled under a reduced pressure, and the residue was separately purified using silica gel column chromatography to obtain 12.9 g of Intermediate 1-2 (Yield: 93%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1,5-Dimethoxynaphthalene, its application will become more common.
Reference:
Patent; Samsung Display Co., Ltd.; Kim, Jong Woo; Kim, Young Guk; Im, Jin Oh; Hwang, Suk Hwan; Kim, Hyung Guen; (58 pag.)KR2015/104678; (2015); A;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem