Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 10075-63-5, name is 1,5-Dimethoxynaphthalene, A new synthetic method of this compound is introduced below., HPLC of Formula: C12H12O2
70% Nitric acid (1.5 mL) in acetic acid (1.5 mL) was addedslowly to a stirred suspension of 1,5-dimethoxynaphthalene(3.76 g, 20 mmol) in acetic acid (50 mL) at room temperature. Upon stirring overnight atambient temperature, the precipitate was filtered offand washed with water. The crude product wasrecrystallized from methanol and dried. Light yellowsolid, yield 85%. 1H NMR spectrum, delta, ppm: 3.92 s(3H), 4.03 s (3H), 6.74 d (J = 8.3 Hz, 1H), 7.01 d (J =7.8 Hz, 1H), 7.44-7.53 m (2H), 7.90 d (J = 8.5 Hz,1H). 13C NMR spectrum, delta, ppm: 56.03, 56.06, 102.24,108.31, 114.68, 117.16, 121.65, 127.15, 127.21,141.18, 153.64, 157.04.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Dong; Zhang; Huang; Meng; Li; Russian Journal of General Chemistry; vol. 87; 4; (2017); p. 837 – 841; Zh. Obshch. Khim.; vol. 87; 4; (2017); p. 837 – 841,5;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem