Some common heterocyclic compound, 578-58-5, name is 2-Methylanisole, molecular formula is C8H10O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Recommanded Product: 2-Methylanisole
a) A solution of 24 g of 2-methylanisole, 35 g of N-bromosuccinimide and 1.24 g of dibenzoyl peroxide in 150 ml of carbon tetrachloride was heated to boiling under reflux for 12 hours. After cooling the solution was filtered and the filtrate is evaporated. The residue was recrystallized from hexane. There were obtained 18.6 g (47%) of 4-bromo-2-methylanisole as a colorless solid; m.p. 66-68.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 578-58-5, its application will become more common.
Reference:
Patent; Hoffmann-La Roche Inc.; US5214046; (1993); A;,
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