Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 88149-49-9, name is 2,6-Dibromo-4-(trifluoromethoxy)aniline, A new synthetic method of this compound is introduced below., Recommanded Product: 88149-49-9
Step one: 0.237 mol,52.63 g of 2-methyl-4-trifluoromethyl-5-thiazolecarboxylic acid(content 95percent)With 0.261 mol,89.2 g of 2,6-dibromo-4-trifluoromethoxyaniline (content 98percent)As for a certain amount of acetonitrile,Warm up to 55°C,Stir for about 0.5 h;Step two:A 0.261 mol catalyst was slowly added dropwise to the above reactants.40 g phosphorus oxychloride,After the addition,Warming to reflux,Insulation reflux reaction,The control was almost complete,The reaction time is about 8 h;Step 3:The above product is lowered to room temperature,Slowly drip it into a certain amount of crushed ice.Then stir for 0.5 h,The target product thiadiamide is obtained.Filter and dry, weigh:112.2 g detected purity: 94.3percent, yield: 84.6percent.
The synthetic route of 88149-49-9 has been constantly updated, and we look forward to future research findings.