Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 89282-70-2, name is 2-Methoxy-2-methylpropan-1-amine, A new synthetic method of this compound is introduced below., Safety of 2-Methoxy-2-methylpropan-1-amine
A mixture of phenyl 5-[(trans-4-{[2-chloro-5-(morpholin-4-yl)phenyl]carbamoyl}cyclohexyl)carbamoyl]-1 H-imidazole-4-carboxylate (100 mg, 0.181 mmol,) and 2-methoxy-2-methylpropan-1 -amine (93 mg, 0.906 mmol, GAS No 89282-70-2) in tetrahydrofuran (4.6 ml) was stirred at 60CC ove r night. For work-up the reaction mixturewas concentrated and purified by preparative HPLG (Method 9) to yield the title compound (5.2 mg, 5% yield).LG-MS (Method 6): R = 1 .08 mm; MS (ESIpos) m/z = 561 .3 [M÷H]. 1HNMR (400 MHz, DMSO-d6): 6 [ppm] = 10.07-9.57 (m, 1H), 9.51-9.04 (m, 2H), 7.35-7.11(m, 3H), 6.81 -6.76 (m, 1H), 3.82-3.61 (m, 5H), 3.15 (s, 3H), 3.13-3.03 (m, 4H), 2.02-1.86 (m,4H), 1.62-1.43 (m, 2H), 1.42-1.27 (m, 2H), 1.13 (s, 6H).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.