Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 5414-19-7, name is 1-Bromo-2-(2-bromoethoxy)ethane, A new synthetic method of this compound is introduced below., Recommanded Product: 5414-19-7
To a dimethylformamide (“DMF”) (50 mL) solution of the product of Part B (6.40 g, 15.2 mmol) was added K2CO3 (6.6 g, 47.8 mmol), 18-crown-6 (1.2 g, 4.5 mmol), and bis(2-bromoethyl)ether (2.8 mL, 22. mmol). The resulting slurry was stirred at 60 C. for 24 hr, and then at room temperature for an additional 16 hr. The solvent was stripped in vacuo, and the residue was partitioned between ethyl acetate (150 mL) and water (100 mL). The organic layer was separated, and the aqueous layer was extracted with EtOAc (3*150 mL) and CH2Cl2 (100 mL). The combined organic layers were dried over MgSO4 and evaporated to form a tan solid. The solid was triturated with diethyl ether, and the precipitate was isolated by filtration and washed with diethyl ether (2*25 mL) to afford 4.79 g (64% yield) of the desired acid in the form of a white solid. LCMS: m/z=513, 515 (M+H).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.