Electric Literature of 4393-09-3, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 4393-09-3 as follows.
EXAMPLE 9a(2) N-(2,3-Dimethoxybenzyl)diethoxyacetamide (Compound 9a(2)) Substitution of 2,3-dimethoxybenzylamine for 2,3-dimethoxy-a-phenethylamine in the foregoing Example provided Compound 9a(2) in 33% yield. 1 H NMR (CDCl3): delta 1.23 (triplet, J=7 Hz, 6H, 2*CH2 CH3); delta 3.63 (quartet, J=7 Hz, 4H, 2*CH2 CH3); delta 3.87 (singlet, 6H, Ar–OCH3); delta 6.88 (multiplet, 3H, Ar–H). IR (neat): 2.99, 3.36, 5.95, 6.33, 6.76mu. Mass spectrum: m/e 297 (M+). Anal. Calculated for C15 H23 NO5: C, 60.59; H, 7.80; N, 4.71. Found: C, 60.19; H, 7.88; N, 4.66.
According to the analysis of related databases, 4393-09-3, the application of this compound in the production field has become more and more popular.