Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 92248-06-1, name is Bis(3-methoxyphenyl)amine, This compound has unique chemical properties. The synthetic route is as follows., category: ethers-buliding-blocks
To a solution of bis(3-methoxyphenyl)amine (1.15g, 5.00mmol) in THF (20mL) at RT was added sodium hydride (60% dispersion in mineral oil, 550mg, 13.8mmol). The suspension was heated to 75C and stirred for 30 min at this temperature. Iodomethane (0.716mL, 11.5mmol) was added within 5 min at 75C and the reaction mixture was continued to stir for 2 h at this temperature. The suspension was treated with water (20mL) and extracted with Et2O (3×65mL). The combined organic layer was dried over Na2SO4 and concentrated in vacuo. Column chromatography on silica gel with pentane:CH2Cl2 3:1 to 1:1 gave 3-methoxy-N-(3-methoxyphenyl)-N-methylaniline (1d) as a yellowish oil (979mg, 81%): Rf 0.64 (CH2Cl2 100%); numax (neat): 2938w, 2834w, 2338w, 1589s, 1489s, 1347w, 1279w, 1221m, 1169w, 1122w, 1046w, 766s, 708w, 631s; 1H NMR (500MHz, CDCl3) delta=7.15-7.19 (2H, m, C5H), 6.62 (2H, ddd, 3J 8.1, 4J 2.2, 0.8, C6H), 6.57-6.58 (2H, m, C2H), 6.52 (2H, ddd, 3J 8.2, 4J 2.5, 0.8, C4H), 3.76 (6H, s, OCH3), 3.29 (3H, s, NCH3); 13C NMR (125MHz, CDCl3) delta=160.5 (C3), 150.2 (C1), 129.8 (C5), 113.3 (C6), 106.7 (C4), 106.6 (C2), 55.2 (OCH3), 40.3 (NCH3); ESI-MS: m/z calcd. for C15H18NO2+ 244.1332 found 244.1330 [M+H+].
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 92248-06-1.