592-55-2, name is 1-Bromo-2-ethoxyethane, belongs to ethers-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. COA of Formula: C4H9BrO
A mixture of (S)-2-({2-[3-(3-hydroxy-phenyl)-propylamino]-4,6-dimethyl-pyrimidine-5- carbonyl}-amino)-3-[(thiophene-2-carbonyl)-amino]-propionic acid (0.20g, 0.40mmol), 2- bromoethyl ethyl ether (0.3 lg, 2.0mmol), sodium iodide (0.30g, 2.0mmol) and triethylamine (0.20g, 2.0 mmol) in DMF (2.5ml) was microwaved at 120C for 20 minutes. The mixture was diluted with EtOAc, washed with brine, dried over Na2S04, filtered, concentrated in the presence of silica gel and chromatographed (30-100% EtOAc in hexane) to give the title compound (124. lmg, 54% yield). MS m/e 570.2 (M+H+).
The synthetic route of 592-55-2 has been constantly updated, and we look forward to future research findings.