In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 592-55-2 as follows. Recommanded Product: 1-Bromo-2-ethoxyethane
In a similar manner 1d was obtained from sodium (diglyme)2 3,4,5-triphenyl-1,2-diphosphacyclopentadienide (0.94 g, 1.52 mmol) and 1-bromo-2-ethoxyethane BrCH2CH2OEt (0.26 g, 1.90 mmol, 25% excess) as a light-yellow oil; yield 0.36 g (59%). 1H NMR (CDCl3): 0.59 (t, 3H, 3JHH = 6.9, 3), 1.42-1.47 (m, 2H, OCH2), 1.51-1.57 (m, 2H, OCH2), 1.88-1.93 (m, 2H, PCH2), 6.85 (d, 4H, 3JHH = 3.42), 6.90 (d, 2H, 3JHH = 7.34), 6.96 (d, 4H, 3JHH = 6.85), 6.99-7.07 (m, 1H, 3JHH = 5.38), 7.20 (d, 2H, 3JHH = 7.34), 7.29 (d, 2H, 3JHH = 5.87). 31P NMR (CDCl3): 51.9 (d, 1JPP = 407.3), 214.1 (d, 1JPP = 407.3). 13 NMR (CDCl3): 16.7 (s, CH3), 25.6 (s, CH2), 27.3 (d, 2JCP = 9.7, CH2), 37.8 (dd, 1JCP = 16.3, 2JCP = 5.8, CH2), 126.4 (s, p-Ph), 126.5 (s, p-Ph), 126.8 (s, p-Ph), 127.4 (s, m-Ph), 128.2 (s, m-Ph), 128.3 (s, m-Ph), 128.5 (s, o-Ph), 129.2 (s, o-Ph), 130.5 (d, 3JCP = 1.4, o-Ph), 131.7 (s, o-Ph), 133.5 (s, o-Ph), 137.6 (d, 3JCP = 6.2, ipso-Ph), 138.24 (dd, 3JCP = 10.4, 3JCP = 3.8, ipso-Ph), 142.8 (d, 3JCP = 9.8, ipso-Ph), 149.7 (ps.tr, 3JCP = 15.51, C4), 164.5 (dd, 1JCP = 7.3, 2JCP = 3.1, C5), 185.8 (dd, 1JCP = 47.1, 2JCP = 14.9, C3).
According to the analysis of related databases, 592-55-2, the application of this compound in the production field has become more and more popular.