In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 36865-41-5, name is 1-Bromo-3-methoxypropane belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. category: ethers-buliding-blocks
[00449] To a 100 mL single-neck flask were added 4-bromo-1 H-pyrazole (3.0 g, 20 mmol), 1-bromo-3-methoxypropane (3.7 g, 24 mmol), cesium carbonate (13 g, 39.90 mmol) and DMF (30 mL). The mixture was heated to 50 C and stirred overnight. The mixture was cooled to rt and to the mixture was added water (50 mL). The mixture was extracted with DC M (50 mL B 4).The combined organic layers were concentrated in vacuo, and the residue was purified by silica gel column chromatography (PE/EA (VN) = 1/1) to give the title compound as colorless oil (4.3 g, 20 mmol, 96%).MS (ESI, pos.ion) m/z: 219.0 [M÷H].
The synthetic route of 36865-41-5 has been constantly updated, and we look forward to future research findings.