Adding a certain compound to certain chemical reactions, such as: 150-78-7, name is 1,4-Dimethoxybenzene, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 150-78-7, COA of Formula: C8H10O2
General procedure: a glass tube was filled with Bi(OTf)3 (0.0328 g, 0.05 mmol), [BMIM]OTf (0.1 g), anisole (0.108 g, 1 mmol), and benzoyl chloride (0.281 g, 2 mmol) and reacted at 120 C for 30 min under microwave activation. After cooling, the mixture was extracted with Et2O (3 × 20 mL). The organic layer was decanted, washed with water (10 mL), aqueous NaHCO3 (2 × 20mL), brine (10 mL), and dried over MgSO4. The solvent was removed using a rotary evaporator. Conversion was determined by GC analysis using n-hexadecane as the internal standard. The isolated yield was determined after purification by flash chromatography (n-hexane, then 10 % EtOAc in n-hexane) to give 4-methoxybenzophenone (0.1993 g, 94 % yield). The purity and authenticity of the product were confirmed by GC-MS and 1H NMR spectroscopy. The same procedure was carried out under conventional heating method.
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