In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 101-55-3, name is 1-Bromo-4-phenoxybenzene belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C12H9BrO
To 260 ml toluene, 108 g para cresol and 80 g 50% caustic lye are added and the water is azeotropically distilled out. To the mass 50 ml DMF, 249 g 4-bromodiphenyl ether and 5 g CuBr are added. The mass is maintained at 150-165C for 6 hrs, cooled to 100C and filtered. The filtrate on fractional distillation gave 235 g (85% yield) of 1-(4-methytphenoxy),4-phenoxybenzene, b.p. 200-201 C/4 mm Hg pr., m.p. -53-54C
The synthetic route of 101-55-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Gharda Chemicals Limited; EP1454891; (2004); A1;,
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