These common heterocyclic compound, 5397-31-9, name is 3-((2-Ethylhexyl)oxy)propan-1-amine, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. COA of Formula: C11H25NO
c) 19.9 parts of the trisazo dyestuffs of part b) above are suspended in 100 parts of water, 10.0 parts of [DIPROPYLENE] glycol monomethyl ether and 4. [8] parts of sodium acetate. After warming at [96C] for over one hour, 5.9 parts of copper sulphate are added in small portions for over one hour, followed by 20.0 parts of 25% ammonia. The mixture is heated to reflux for 12 hours whereupon a voluminous suspension of the copper complex results. The temperature is allowed to fall to [45C] over 2 hours (while stirring well) and the suspension is slowly reacted with a solution of 13.3 parts of [3-[(2-ETHYLHEXYL) OXY]-1-] propanamine in 70 parts of water and [8.] 3 parts of 30% HCI. The resulting precipitate is stirred a further hour at room temperature, filtered and the residue is washed salt free and dried. A compound of formula wherein R is methoxy, is obtained.
The synthetic route of 3-((2-Ethylhexyl)oxy)propan-1-amine has been constantly updated, and we look forward to future research findings.
Reference:
Patent; CLARIANT INTERNATIONAL LTD; WO2003/99937; (2003); A1;,
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