Synthetic Route of 24743-14-4, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 24743-14-4 name is 3-(3-Methoxyphenyl)-1-propene, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
EXAMPLE 1; Typical procedure for the stoichiometric conversion of alkenes to alkylene carbonates using NBS and DBU[0054] NBS (266 mg, 1.5 mmol) was added to a vial comprising a magnetic stirrer, and partially dissolved using water (1 ml_). DBU (0.35 ml_, 2.4 mmol) was added to the mixture using a syringe, followed by the immediate addition of the alkene (1.5 mmol). The reaction mixture was not stirred until the onset of the reaction. The vial was then placed in a stainless steal autoclave (Parr reactor) which was pressurized with CO2 at an overall pressure of 250 psi. The reactor was not purged prior to pressurization. The reaction temperature was maintained at about 40 to about 6O0C (depending on the nature of the alkene) using a Parr temperature controller. After 2-6 hours of reaction time (depending on the nature of the alkene), the reactor was cooled to room temperature and depressurized. Ethyl acetate (1 ml_) was used to extract the organic material. Following purification by flash chromatography, the product was characterized by 1H and 13C NMR.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3-(3-Methoxyphenyl)-1-propene, and friends who are interested can also refer to it.
Reference:
Patent; MCGILL UNIVERSITY; WO2008/34265; (2008); A1;,
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