Reference of 5414-19-7, The chemical industry reduces the impact on the environment during synthesis 5414-19-7, name is 1-Bromo-2-(2-bromoethoxy)ethane, I believe this compound will play a more active role in future production and life.
To a room temperature mixture of the tert-butyl [2- [ (4-BROMOPHENYL) SULFONYL]] acetate (2) from Part A (0.25 mol) in 100 mL dimethyl formamide (“DMF”) was added 18-crown-6 (19.4 g, 0.07 mol), potassium carbonate [(“K2CO3”)] (169 g, 1.22 mol), and bis (2- bromoethyl) ether (62.5 g, 0.27 mol). The mixture was stirred at room temperature for 18 hr, after which time no starting material (2) was detected by HPLC. The resulting mixture was concentrated, diluted in 500 mL ethylacetate [(“CH3COOC2HS”OR”ETOAC”),] and filtered. The resulting filtrate was concentrated to produce a yellow oil that solidified upon standing to afford the desire product (3). LCMS: [M+Na] = 427.05.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Bromo-2-(2-bromoethoxy)ethane, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; PHARMACIA CORPORATION; WO2004/811; (2003); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem