Application of 39538-68-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 39538-68-6, name is 2-Methoxy-4-methylaniline belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
General procedure: Malonyl diamide derivatives were prepared as described earlier.49 Briefly: To a magnetically stirred ice bath-cooled solution of the selected amine (14 mmol), and triethylamine (14 mmol, 1.4 g) in dioxane (20 ml), malonyl dichloride (1.0 g, 7.0 mmol) solution in dioxane (20 ml) was added dropwise over 15 min. The reaction mixture was stirred at 0 C for one hour. Subsequently, HCl (2 N, 50 ml) was added to the reaction suspension and stirred for 30 minutes. Finally, the mixture was filtered to afford the products as whitish to gray solids that were further washed by stirring in water (50 mL) for 30 min (Scheme 1).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Methoxy-4-methylaniline, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Habash, Maha; Taha, Mutasem O.; Bioorganic and Medicinal Chemistry; vol. 19; 16; (2011); p. 4746 – 4771;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem