Discovery of 171290-52-1

According to the analysis of related databases, 171290-52-1, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 171290-52-1, name is 3,5-Dimethoxyphenylacetylene, This compound has unique chemical properties. The synthetic route is as follows., Formula: C10H10O2

General procedure: The azido-sugar 2(1 equiv) was dissolved in dry THF (45 mL/mmol) and the required alkyne derivative (5.4 equiv), diisopropylethylamine(1.9 equiv), CuI (0.57 equiv) and DMEDA (5.2 equiv) were added. The reaction mixture was heated to reflux until TLC indicated complete consumption of 2, then the solvent was removed.The residue was dissolved in EtOAc and washed with H2O twice and once with an aqueous solution of EDTA (1%,m/v). The organic layer was dried over MgSO4, filtered and the solvent removed. Purification of the crude material on column chromatography on silica gel (CH2Cl2/EtOAc) afforded the desired product

According to the analysis of related databases, 171290-52-1, the application of this compound in the production field has become more and more popular.

Reference:
Article; Van Nguyen, Tai; Hospital, Audrey; Lionne, Corinne; Jordheim, Lars P.; Dumontet, Charles; Perigaud, Christian; Chaloin, Laurent; Peyrottes, Suzanne; Beilstein Journal of Organic Chemistry; vol. 12; (2016); p. 1476 – 1486;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem