Synthetic Route of 944561-44-8, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 944561-44-8, name is 2-[2-(2-Propynyloxy)ethoxy]ethylamine, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: To a solution of compound 7 (200 mg, 0.34 mmol) and terminalalkynyl substituted amine (0.43 mmol) in DMF (10 mL), Na2CO3(72 mg, 0.68 mmol) was added. The resulting solution was vigorouslystirred for 24 h at 60 C. The solvent was removed bysteaming. The residue was purified by column chromatography.
The chemical industry reduces the impact on the environment during synthesis 2-[2-(2-Propynyloxy)ethoxy]ethylamine. I believe this compound will play a more active role in future production and life.
Reference:
Article; Liang, Shuobin; Li, Man; Yu, Xiaojuan; Jin, Hongwei; Zhang, Yongmin; Zhang, Lihe; Zhou, Demin; Xiao, Sulong; European Journal of Medicinal Chemistry; vol. 166; (2019); p. 328 – 338;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem