Synthetic Route of 1515-89-5, A common heterocyclic compound, 1515-89-5, name is 1-Bromo-3-(methoxymethyl)benzene, molecular formula is C8H9BrO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
PREPARATION 103 3-Methoxymethylphenylboronic Acid Obtained as a yellow solid (100%), from 1-bromo-3-methoxymethylbenzene (J. Amer. Chem. Soc., 1989, 111, 6311; Tetrahedron 1985, 41, 1435) and trimethyl borate1 using the procedure of Preparation 101. delta(DMSOd6): 3.27 (s,3H), 4.38 (s,2H), 7.31 (m,2H), 7.68 (m,2H), 7.98 (brs,2H).
The synthetic route of 1515-89-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Pfizer INC; US6387931; (2002); B1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem