Electric Literature of 2393-23-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2393-23-9, name is 4-Methoxybenzylamine belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
To a solution of p-anisaldehyde (146 mmol) in ethanol (500 mL) was added 4- methoxybenzylamine (146 mmol). The mixture was then cooled in an ice water bath. NaBH4 (294 mmol) was added in portions and the reaction mixture was allowed to warm to rt, gradually. Ice water slush (100 mL) was added and the mixture was concentrated to half its original volume. The mixture was then extracted with ether and the organics were combined, washed with brine, dried, and concentrated. Hexane (~50 mL) was added and the precipitate was filtered to give 35 g of bis-(4-methoxy-benzyl)-amine, 19, as white solid.
The synthetic route of 4-Methoxybenzylamine has been constantly updated, and we look forward to future research findings.
Reference:
Patent; IRM LLC; WO2006/81554; (2006); A2;,
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