Adding a certain compound to certain chemical reactions, such as: 366-99-4, name is 3-Fluoro-4-methoxyaniline, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 366-99-4, COA of Formula: C7H8FNO
General procedure: The procedure was performed adopting literature.46 To a solutionof ArNH2 (3, 5 mmol, dissolved in 10 mL acetic acid), wasadded aquatic solution of NaOCN (7.5 mmol, 7.5 mL). The mixturewas allowed to be stirred at room temperature for 1 h and thenconcentrated under reduced pressure. Afterwards, saturatedK2CO3 solution was added to adjust the pH to 7?8. A large scaleof precipitate was therefore formed, which was then filtered,washed with water for several times and then recrystallized fromMeOH – DCM
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Reference:
Article; Zhang, Mao; Liang, Yu-Ru; Li, Huan; Liu, Ming-Ming; Wang, Yang; Bioorganic and Medicinal Chemistry; vol. 25; 24; (2017); p. 6623 – 6634;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem