Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 7025-06-1, name is 1-Bromo-2-phenoxybenzene, A new synthetic method of this compound is introduced below., Recommanded Product: 1-Bromo-2-phenoxybenzene
31.7 g (127 mmol) of1-Bromo-2-diphenyl ether,Dissolve in 400 ml of anhydrous THF in a flask which has been dried by heating. Cool the reaction mixture to -78 ¡ã C. At this temperature 55 ml of a 2.5 M solution of n-BuLi in hexane (127 mmol) is slowly added dropwise.The batch was further heated at -70 ¡ã C.Stir for 1 hour.30 g of 2-bromofluorenone (116 mmol)Is dissolved in 100 ml of THF and added dropwise at -70 ¡ã C.Upon completion of the addition, the reaction mixture is warmed slowly to room temperature, warmed up using NH 4 Cl, then evaporated in a rotary evaporator.
The synthetic route of 7025-06-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; MERCK PATENT GMBH; MUJICA-FERNAUD, TERESA; MONTENEGRO, ELVIRA; VOGES, FRANK; KROEBER, JONAS VALENTIN; STOESSEL, PHILIPP; (98 pag.)JP2016/505518; (2016); A;,
Ether – Wikipedia,
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