A common compound: 111-95-5, name is Bis(2-methoxyethyl)amine, belongs to ethers-buliding-blocks compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below. 111-95-5
General procedure: General procedure B: To a mechanically stirred solution of bis(2-methoxyethyl)amine (39.96 g, 0.3 mol) in dichloromethane (100 mL), was added dropwise n-butyllithium (1.6 M in n-hexane, 187.5 mL, 0.3 mol) at -78 C under an argon atmosphere. After further stirring for 5 min, pentafluoroethanesulfonyl fluoride (2, 20.21 g, 0.1 mol) was added and the mixture was stirred for 1 h. Then the cryopump was removed, and allow the mixture stand at room temperature. The subsequent procedures exactly followed those in the procedure A.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 111-95-5, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Fu, Shi-Tao; Liao, Shuai-Ling; Nie, Jin; Zhou, Zhi-Bin; Journal of Fluorine Chemistry; vol. 147; (2013); p. 56 – 64;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem